The Retrospective Brain Imaging in Dementia study
Research type
Research Study
Full title
A Retrospective Brain Imaging in Dementia study - improving diagnosis and reporting standards using cross-sectional and longitudinal analysis methods
IRAS ID
163935
Contact name
Angus Prosser
Contact email
Sponsor organisation
University Hospital Southampton NHS Foundation Trust
Duration of Study in the UK
1 years, 5 months, 30 days
Research summary
Timely diagnosis for dementia patients has been shown to lead to better patient and carer clinical outcomes and improved quality of life. Improving dementia diagnosis rates has been one of the main objectives in numerous recent national and international policies and reports on dementia (National Dementia Strategy, 2009; National Health Service ‘Improving care for people with dementia’ policy, 2013; UK Prime Ministers Dementia Challenge, 2012; G8 dementia summit, 2013; World Alzheimer report, 2011). However, Diagnosis of dementia and prediction of decline in individuals with cognitive complaints remains difficult, as symptoms, cognitive deficits and imaging pathology commonly vary between patients. Early diagnosis and identification of individuals at highest risk of decline is essential for signposting patients to appropriate care resources.
This study aims to maximise the use of data previously acquired during routine clinical care and improve diagnostic and prognostic accuracy in dementia clinical practice. The study will use pseudonymised retrospective data analysis to study the value of imaging, fluid biomarkers and neuropsychological tests in a cognitively impaired group.
This study is an observational retrospective pseudonymised data only study, and as such there is no recruitment to the study. No patient identifiable data will be accessed by the study researchers.
REC name
North East - Tyne & Wear South Research Ethics Committee
REC reference
14/NE/1252
Date of REC Opinion
10 Dec 2014
REC opinion
Favourable Opinion