The RETRAIN Trial (PHASE 1)
Research type
Research Study
Full title
MonitoRing the Effect of TRAnscutaneous functional electrIcal stimulation of the common peroneal Nerve on cerebral haemodynamics in patients with ischaemic strokes. A single centre prospective study.
IRAS ID
343056
Contact name
Kausik Chatterjee
Contact email
Sponsor organisation
Countess of Chester NHS Foundation Trust
Duration of Study in the UK
0 years, 5 months, 0 days
Research summary
Ischaemic strokes, caused by a disruption in the brain's blood supply, are the second leading cause of death and disability in the United Kingdom. This single-center prospective study aims to measure blood flow and oxygen delivery to the brain in patients who have recently suffered from an ischaemic stroke and who are wearing the geko™ neuromuscular device as part of their routine clinical care.
The geko™ device operates by stimulating a nerve in the lower leg, which in turn induces muscle contractions that enhance blood circulation. The principal objective of this research is to determine the optimal stimulation settings and postural positions that elicit the maximum efficacy of the geko™ device in augmenting blood and oxygen flow to the brains of stroke survivors. This will be measured using functional near-infrared spectroscopy (fNIRS).
We intend to investigate the effects of the geko™ device on cerebral blood flow in adult stroke patients who are more than seven days post-stroke onset. Eligible participants are those who consent to the study, qualify to receive the geko™ device as part of their routine clinical care and are capable of maintaining a sitting or a semi-sitting position at a 45-degree angle.REC name
London - Bloomsbury Research Ethics Committee
REC reference
24/LO/0436
Date of REC Opinion
13 Aug 2024
REC opinion
Further Information Favourable Opinion