The Research Tissue Bank, Envigo CRS (Contract Research Services)

• Research type

  Research Tissue Bank

• IRAS ID

  261997

• Research summary

  The Research Tissue Bank, Envigo CRS (Formerly Huntingdon Life Sciences)

• REC name

  Yorkshire & The Humber - Sheffield Research Ethics Committee

• REC reference

  19/YH/0091

• Date of REC Opinion

  15 Apr 2019

• REC opinion

  Unfavourable Opinion

• Data collection arrangements

  The Research Tissue Bank, Envigo CRS will be situated at the main site at Alconbury and a smaller collection of tissues at the Envigo site in Eye, Suffolk, and Shardlow Derbyshire.
  Depending on the individual research study requirements a wide range of tissues will include but not be restricted to:
  Full-thickness skin surplus at therapeutic intervention
  Normal and disease conditions plus blood and urine where required eg Crohn’s disease
  Cancer and associated normal tissue eg Lung tissue at therapeutic intervention.
  Tissues snap frozen and stored at -80°C
  DNA, RNA subcellular or protein extracts at -80°C
  Primary cell cultures in culture flasks containing culture medium eg keratinocytes
  Primary cell suspension and cellular subfractions at -80°C eg hepatocytes and microsomes
  Formalin fixed and paraffin embedded tissues stored at room temperature
  Associated data and data access:
  The associated data will reflect the minimal dataset of age, gender and any associated requested information such as lifestyle questions eg smoking details, alcohol consumption and main occupation.
  All tissues collected for the tissue bank will have ethical approval and donor consent.

• Research programme

  Envigo CRS conducts a wide range of research types across many fields of biomedicine. As a Contract Research Organisation it responds to the external Sponsors request for research into both animal and increasingly to confirm findings from animal studies in human tissue. Additionally, external Sponsors are requesting research studies in clinical tnal samples from human volunteers. The types of research that will be conducted include but will not be restricted to: In vitro drug metabolism pharmacokinetic studies; tissue-cross reactivity and immunohistochemical studies; toxicology studies; bio-analytical studies and microbiological studies.

• Storage license

  12400

• RTBTitle

  The Research Tissue Bank, Envigo CRS (Formerly Huntingdon Life Sciences)

• Establishment organisation

  Envigo CRS

• Establishment organisation address

  Shardlow Business Park ,

  London Road

  Derby

  DE72 2GD