The RELIABLE Study
Research type
Research Study
Full title
REtinaL Imaging & Ambulatory BLood PrEssure: validating ultra-widefield retinal imaging derived biomarkers against ambulatory blood pressure
IRAS ID
228069
Contact name
Iain MacIntyre
Contact email
Sponsor organisation
NHS Lothian
Duration of Study in the UK
0 years, 11 months, 31 days
Research summary
High blood pressure is a common condition which generally does not have any symptoms. Its estimated that around one third of people with high blood pressure do not know they have it. The back of the eye called the retina is one of the few places in the human body allowing easy observation of blood vessels. This study aims to see if simple non-invasive imaging of the blood vessels of the retina will highlight people with high blood pressure.
This will be a prospective, single centre study recruiting patients who are attending the ambulatory blood pressure clinic at the Western General Hospital. Suitable patients will be approached, and if they consent will have pictures of the back of each of their eyes taken. These pictures will then be reviewed, with certain measurements taken of the small blood vessels which can been seen at the back of the eye. These measurements will then be compared to the participants blood pressure readings to see if they might accurately correlate to blood pressure.
REC name
South Central - Hampshire B Research Ethics Committee
REC reference
18/SC/0620
Date of REC Opinion
7 Nov 2018
REC opinion
Favourable Opinion