The relationship between BMI and CSF opening pressure
Research type
Research Study
Full title
Determining the relationship between body mass index and cerebrospinal fluid opening pressure in patients undergoing elective lumbar puncture
IRAS ID
135095
Contact name
Rajiv Mohanraj
Contact email
Research summary
This study aims to assess whether a relationship exists between body mass index (BMI) and the pressure of the fluid which surrounds the brain and spinal cord (cerebrospinal fluid or ’CSF’). This so called ’opening pressure’ can be measured by performing a lumbar puncture, a diagnostic procedure routinely undertaken in the hospital setting to determine whether a patient is suffering from a neurological condition. This study will also aid in the determination of the normal range for CSF opening pressures in patients being treated at the Greater Manchester Neurosciences Centre, Salford Royal NHS Foundation Trust. In addition, data collected through this study will determine the success rate of the lumbar puncture procedure, the rate and type of complications, and assess the completeness of associated documentation.
The aims of this study will be achieved through the analysis of routine clinical data which exist in patient notes. The notes of approximately 400 patients will be reviewed and relevant data extracted to be analysed by members of the immediate care team.
REC name
London - Fulham Research Ethics Committee
REC reference
13/LO/1673
Date of REC Opinion
22 Oct 2013
REC opinion
Favourable Opinion