The Rare Disease Registry Program (Gaucher, Fabry, Pompe, MPS1) Amd 11 - RENEWAL

  • Research type

    Research Database

  • IRAS ID

    341912

  • Contact name

    Simon Jones

  • Contact email

    Simon.Jones@cmft.nhs.uk

  • Research summary

    The Rare Disease Registry Program (The X-Registries)

  • REC name

    North West - Greater Manchester Central Research Ethics Committee

  • REC reference

    24/NW/0102

  • Date of REC Opinion

    3 Jul 2024

  • REC opinion

    Further Information Favourable Opinion

  • Data collection arrangements

    This is a long term ongoing non-interventional observational program (there is currently no end date) As an observational database it tracks the natural history and outcomes of patients with Pompe, Fabry, Gaucher and MPS1 Disease. The primary purpose of the Registry program is to collect uniform and meaningful clinical data on patients with rare disease.
    Each Registry Program is specifically centered around that particular disease and is focused on collecting key standard of care assessments and clinical outcomes associated with that diseases management.

  • Research programme

    The objectives of the Registry Program are to enhance the understanding of the variability, progression, and natural history of these diseases with the ultimate goal of better guiding and assessing therapeutic intervention; to assist the medical community treating patients with these diseases with recommendations for monitoring patients and reports on patient outcomes to optimize patient care; to characterize disease populations and to evaluate the long-term safety and effectiveness of Enzyme Replacement Therapy (ERT). Data from the Registry are also used to fulfil various global regulatory commitments, to support product development/reimbursement, and for other research and non-research-related purposes.

  • Research database title

    The Rare Disease Registry Program (The X-Registries)

  • Establishment organisation

    Sanofi B.V.

  • Establishment organisation address

    Paasheuvelweg 25

    Amsterdam

    NETHERLANDS

    1105 BP