The psychological impact of a dietary intervention on mood. Version 1
Research type
Research Study
Full title
The psychological impact of eating sourdough bread compared to industrial store-bought bread: a single case experimental design (SCED).
IRAS ID
343924
Contact name
Jamie-Lee Cronje
Contact email
Sponsor organisation
Royal Holloway, University of London
Duration of Study in the UK
1 years, 2 months, 30 days
Research summary
In nutritional psychiatry, good mental health is supported by eating foods that nourish your gut microbiome, such as fermented foods, fibre, and a diverse range of plants. When the gut is undernourished, it can result in the chemicals we need for healthy brain function to be reduced, leading to poor mental health (e.g. depression). Recent studies indicate people who suffer with poor mental health could have impaired gut health. Depression is usually treated with psychological therapy or medication; however, the role of gut health is not considered in these treatment options. This study aims to look at the impact of one element of a novel intervention, the Baking as Lifestyle Medicine (BALM) protocol. The element being evaluated is the consumption of sourdough bread (a fermented product high in fibre and plant diversity) compared to mass manufactured low-quality bread and what impact this has on symptoms of depression. Data gathered from the study will develop the current knowledge and build new evidence for the BALM protocol, which could be routinely offered to patients if the intervention is effective. Participants will be eligible if they are over 18 years old and have depression. Participants will be offered one individual session with the chief investigator to conduct a clinical assessment, explain the study and ask any questions prior to being enrolled. Recruitment will be facilitated through Greenview GP in Northampton. The study is 20 weeks in total, including baseline and intervention phases. Participants will be required to consume bread daily for 16 weeks during the intervention phases. The bread will be sent directly to their home, there is no requirement for them to attend any sites in person following enrolment. They will also be required to complete daily and weekly questionnaires throughout the study.
REC name
London - Surrey Research Ethics Committee
REC reference
24/LO/0515
Date of REC Opinion
26 Jul 2024
REC opinion
Further Information Favourable Opinion