The PRIME Study: Positive tRansItions through the MEnopause
Research type
Research Study
Full title
The PRIME Study: Positive tRansItions through the MEnopause
IRAS ID
177383
Contact name
Shema Tariq
Contact email
Sponsor organisation
Joint Research Office (part of the Research Support Centre)
Clinicaltrials.gov Identifier
Z6364106/2015/04/38, UCL Data Protection Registration
Duration of Study in the UK
1 years, 11 months, 22 days
Research summary
The number of women accessing HIV care aged 45-56 (potentially menopausal age) has increased from around 400 in 2000, to over 7500 in 2013, nearly a third of all women accessing HIV care. The menopause can cause a range of symptoms, impacting on women's day-to-day lives. There is a lack of data on menopause in HIV-positive women. We are conducting the first large-scale study in the UK on HIV and menopause. We aim to explore the impact of the menopause on HIV-positive women's wellbeing and health.
We will:
(1) describe how common menopause and menopausal symptoms are in HIV-positive women
(2) explore the relationship between menopause and menopausal symptoms, and the following: mental health, sexual problems, quality of life, use of HIV medication, HIV clinic attendance, and condom use
(3) explore HIV-positive women’s experiences of menopause and map current management of symptoms in this group.This study of 1500 HIV-positive women recruited from 15 NHS sites throughout England will combine quantitative and qualitative approaches. We will administer questionnaires to participants and collect data from clinic databases. We will conduct in-depth interviews with a proportion of participants. We will seek permission to follow-up participants. This work will identify unmet clinical need and address important public health questions, informing the care of this growing population.
REC name
London - Surrey Research Ethics Committee
REC reference
15/LO/2051
Date of REC Opinion
9 Dec 2015
REC opinion
Favourable Opinion