The MyoPAD study (version number 3)
Research type
Research Study
Full title
The Myositis Physical Activity Device Study
IRAS ID
235375
Contact name
Hector Chinoy
Contact email
Sponsor organisation
University of Manchester
Duration of Study in the UK
1 years, 7 months, 29 days
Research summary
What is the context of the MyoPAD study?\nThe idiopathic inflammatory myopathies (IIMs) are a group of diseases that cause inflammation of the muscles of affected sufferers, which results in irreversible damage and disability. \nInfrequent assessment at hospital appointments (typically 6 monthly) risks late identification of worsening disease activity. Therefore, accurate identification of the occurrence of worsening disease activity through more frequent assessment is key to guiding a clinician’s timely decision to instigate treatments.\nThe ability to continuously and remotely assess a patient’s IIM disease activity is currently not available and could greatly enhance treatment instigation decisions.\nIIM disease activity is associated with changes in patient reported outcome measurements (PROMs), which can be collected via smartphone-based “apps”, and changes in walking pattern, which can be measured via small, user friendly, wearable “accelerometer” devices.\n\nWhat is the research trying to achieve?\nThis study aims to see if PROMs collected via a smartphone app and walking pattern measured via an accelerometer can detect changes in IIM disease activity.\n\nHow will the study be conducted?\nParticipants with an IIM will be recruited from Greater Manchester NHS hospitals to participate in the co-design of a smartphone-based “app” for PROM entry and an accelerometer patch system. Data will be collected in a subsequent 3 month data collection period. The data collection period will entail two components for participants: 1 – entering PROM information through a smartphone-based app on a daily basis, 2 – continuously wearing a small accelerometer “patch” that can continuously and remotely measure walking pattern.\nSubtle longitudinal changes in patterns of PROMs and walking pattern will be identified through analysis.
REC name
North West - Greater Manchester South Research Ethics Committee
REC reference
18/NW/0676
Date of REC Opinion
6 Dec 2018
REC opinion
Further Information Favourable Opinion