The Manchester Pregnairclean Study
Research type
Research Study
Full title
The Manchester Pregnairclean Study
IRAS ID
250365
Contact name
Andrew Povey
Contact email
Sponsor organisation
The University of Manchester
Clinicaltrials.gov Identifier
N/A, No suitable register exists
Duration of Study in the UK
1 years, 2 months, 31 days
Research summary
Indoor air quality (IAQ) refers to the quality of air in a particular building or structure. Adverse IAQ may result in negative effects on the health of the occupants of that building. In particular, it has been associated with adverse pregnancy outcomes and it has been suggested that the most influential environmental factor affecting pregnancy is home IAQ (Ghosh et al., 2013). Whilst some studies have described associations between IAQ and adverse pregnancy outcomes, clinical evidence identifying the underlying biological mechanisms is limited and the aetiology is unclear (Glinianaia et al., 2004; Patelarou and Kelly, 2014). In developed countries, there is public health legislation on both building construction and quality (Patelarou and Kelly, 2014). Therefore, it would be useful to examine the combination of factors such as sources of pollution and indoor daily activities of pregnant women (e.g. cooking, exposure to smoke) locally.
There is a lack of such studies in Manchester. This proposed work will not only determine the feasibility of such study but will also help to examine the potential scale and range of the problem in Greater Manchester. The overall aim of this study will be to better understand the association between IAQ and adverse pregnancy outcomes, by focusing on the measurement of indoor air particles (particulate matter). This study will focus on the feasibility of measuring indoor air particles in the homes of pregnant women across Greater Manchester and the collection and analysis of biological samples (placenta, maternal and cord blood).
REC name
East Midlands - Leicester South Research Ethics Committee
REC reference
18/EM/0317
Date of REC Opinion
25 Oct 2018
REC opinion
Further Information Favourable Opinion