The Manchester Paediatric AKI Study
Research type
Research Study
Full title
A multi-centre prospective cohort study to ascertain the incidence of acute kidney injury (AKI) in children presenting to hospital with suspected septic shock.
IRAS ID
203144
Contact name
Rachael O Barber
Contact email
Sponsor organisation
Manchester NHS Foundation Trust
Duration of Study in the UK
0 years, 11 months, 31 days
Research summary
When children get infections some of them become very unwell (referred to by doctors as sepsis or septic shock). A number of things happen to the body when children are septic, including low blood pressure, and low blood flow to organs including the kidneys. This can cause kidney damage, which is referred to as Acute Kidney Injury. This is well recognised in children who are so sick that they need intensive care, but there are a large number of children who go to hospital, get treated with fluids and antibiotics and get better, thus never needing intensive care. The frequency and degree of kidney damage in these children is unknown, but important because even mild kidney damage in childhood may lead to long term kidney disease in later life.
REC name
Yorkshire & The Humber - Leeds West Research Ethics Committee
REC reference
16/YH/0425
Date of REC Opinion
6 Oct 2016
REC opinion
Further Information Favourable Opinion