The Intensive Care Muscle Imaging ('I C Muscle') Study
Research type
Research Study
Full title
A pilot observational study to investigate the structure and function of skeletal muscle in survivors of critical illness using magnetic resonance imaging.
IRAS ID
165265
Contact name
David Griffith
Contact email
Duration of Study in the UK
1 years, 6 months, 1 days
Research summary
We will use a technique called magnetic resonance imaging (MRI) to non-invasively study the volume, structure, and function of the muscles of patients that have survived an intensive care unit admission in order to further understand the reasons for damage, and failure to recover function. 3 groups of patients will be studied: the first group will be patients that have survived an intensive care admission who are still very weak in the first 7 days after ICU discharge. The second group will be patients that have survived an intensive care admission who have regained strength in the first 7 days after ICU discharge. The 3rd group will be an elective surgical control group who are known to have good physical function. Various MRI parameters will be compared including measures of muscle volume, muscle quality, and muscle stiffness to assess whether these MRI findings explain the clinical findings of weakness, and to explore how they related to traditional methods of assessment (i.e. ultrasound scanning).
REC name
South East Scotland REC 02
REC reference
15/SS/0056
Date of REC Opinion
14 Apr 2015
REC opinion
Further Information Favourable Opinion