The Influence Of Body Composition On Clinical Outcomes in Crohn's

  • Research type

    Research Database

  • IRAS ID

    166341

  • Contact name

    Nik Ding

  • Contact email

    nik.ding@nhs.net

  • Research summary

    The Influence Of Body Composition On Clinical Outcomes in Patients with Crohn’s Disease

  • REC name

    London - South East Research Ethics Committee

  • REC reference

    14/LO/2110

  • Date of REC Opinion

    9 Jan 2015

  • REC opinion

    Further Information Favourable Opinion

  • Data collection arrangements

    This study aims to establish the relationship between body composition i.e the proportion of fat and muscle in a human body and surgical outcomes in patients with Crohn's disease. The study population of this research project includes all patients that were treated for Crohn's disease from 2007 to 2014 at LNWH NHS trust. The data counted in in the study are: Demographic, pathology, surgical, medical therapy, body composition, imaging and follow up data. All identifiable information will be anonymised prior to storage in password-locked NHS computers. Only members of the research team will have access to these stored data.

  • Research programme

    We will perform an observational study, aiming to answer the question regarding the relationship between body composition and Crohn's disease. We will test whether body composition is associated with progression of disease and clinical outcomes. If it is identified that the body composition, a modifiable condition of a patient undergoing treatment for Crohn's is related to the prognosis and the outcomes of disease, it is likely to confer multiple benefits to both Crohn's patients and the National Health Service.

  • Research database title

    The Influence Of Body Composition On Clinical Outcomes in Patients with Crohn’s Disease

  • Establishment organisation

    London North West Healthcare NHS Trust

  • Establishment organisation address

    Northwick Park Hospital

    Watford Road

    Harrow

    HA1 3UJ