The Feasability of Endoscopic Ultrasound-Guided Portal Vein Manometry
Research type
Research Study
Full title
The Feasability of Endoscopic Ultrasound-Guided Portal Vein Manometry (EUS)
IRAS ID
180187
Contact name
Kofi Oppong
Contact email
Sponsor organisation
The Newcastle Upon Tyne Hospitals NHS Foundation Trust
Duration of Study in the UK
0 years, 5 months, 0 days
Research summary
The portal vein is a blood vessel that conducts blood from the gastrointenstinal tract and spleen to the liver. Having an accurate measurement of the difference between the pressure in the portal vein and that of the hepatic vein in patients with chronic liver disease is important when deciding upon best treatment.
However, this measurement is not often made as the currently available test to make the measurement is involved and complex. Plus it can potentially lead to complications resulting from under-treatment in some patients and over-treatment in others.
What we want to do is trial the use Endoscopic Ultrasound (EUS) to help us make this measurement. Using EUS enables an excellent view of the portal vein and hepatic vein from within the stomach. When placed in the stomach the tip of the EUS is within a few centimetres of the portal and hepatic veins. Under EUS control the veins can be punctured allowing the pressure within to be accurately measured.REC name
North East - Tyne & Wear South Research Ethics Committee
REC reference
15/NE/0310
Date of REC Opinion
6 Nov 2015
REC opinion
Further Information Favourable Opinion