The ExSEAL study

• Research type

  Research Study

• Full title

  The ExSEAL Study: Ex-vivo assessment of vessel SEALing and lateral thermal spread using advanced energy devices in inflammatory tissues.

• IRAS ID

  364958

• Contact name

  Christopher Challand

• Contact email

  christopher.challand@nhs.net

• Sponsor organisation

  University of Sheffield

• Duration of Study in the UK

  2 years, 0 months, 1 days

• Research summary

  Energy devices are used ubiquitously in many surgical specialties. They function by imparting thermal energy to tissues, causing water vaporization, coagulation and tissue sealing. There is no evidence regarding their use in inflammatory tissues, which by definition have a greater water content within. This study aims to assess the changes to vessel sealing and lateral thermal spread between normal and inflammatory tissues when using these devices.

• REC name

  London - London Bridge Research Ethics Committee

• REC reference

  26/PR/0090

• Date of REC Opinion

  23 Feb 2026

• REC opinion

  Further Information Favourable Opinion