The European NAFLD Registry

• Research type

  Research Study

• Full title

  The European NAFLD Registry

• IRAS ID

  229678

• Contact name

  Quentin Anstee

• Contact email

  quentin.anstee@newcastle.ac.uk

• Duration of Study in the UK

  4 years, 11 months, 31 days

• Research summary

  Aim: To validate a range of non-invasive biomarkers that will grade/stage liver disease in patients with NAFLD.

  Plan: Recruit patients undergoing clinically indicated liver biopsies for NAFLD, collect additional blood samples, urine samples and stool samples for research use. Administer questionnaires (dietary, exercise, wellbeing/symptoms). Collect data from routine investigations from medical notes. Follow patients longitudinally at 1-year intervals, collecting additional samples, etc.

  A subset of patients participating in the European NAFLD Registry may opt-in to a nested imaging study using ultrasound and MRI (i.e. NO study-related x-ray exposure or administration of contrast agents). This imaging study will involve a separate IRAS application and informed consent but data may be shared with the current project.
  

• REC name

  North East - Tyne & Wear South Research Ethics Committee

• REC reference

  18/NE/0182

• Date of REC Opinion

  2 Jul 2018

• REC opinion

  Favourable Opinion