The EQuIP Study
Research type
Research Study
Full title
Development and validation of Emerging Quantitative Imaging techniques for assessing myocardial Perfusion - The EQuIP Study
IRAS ID
276543
Contact name
Amedeo Chiribiri
Contact email
Sponsor organisation
King's College London
Duration of Study in the UK
1 years, 2 months, 30 days
Research summary
Cardiac magnetic resonance imaging (CMR) is recognised as one of the imaging methods of choice to investigate the heart. A technique called stress perfusion CMR, which involves giving patients a medication to increase their heart rate, is used to identify the diagnosis of chest pain. This allows the investigation of coronary artery disease (CAD)and problems with smaller blood vessels called microvascular disease (MVD), and differentiates these form other causes of chest pain such as structural changes of the heart (called cardiomyopathy) or inflammation of the heart muscle (called myocarditis).
A dedicated team at King's College London and Guy's & St Thomas' NHS Foundation Trust have been involved in improving the diagnosis from stress perfusion CMR for the past decade. This research is an extension of this work, in a bid to improve comparability of data between different scanners, repeatability of methods and accuracy of emerging techniques in stress perfusion CMR.
This study invites patients who are already being investigated for suspected cardiac issues via stress CMR to have a second comparable scan. This could be done on a different scanner or with methods not previously used during clinical scanning. This would allow new techniques to be tested and validated against existing methods used in clinical practice. Participation in the study is purely voluntary and all study data would be processed and stored anonymously to maintain patient confidentiality.
REC name
North West - Haydock Research Ethics Committee
REC reference
22/NW/0188
Date of REC Opinion
24 Jun 2022
REC opinion
Unfavourable Opinion