The EPIC-Norfolk Fifth Health Check (5HC)
Research type
Research Study
Full title
The European Prospective Investigation of Cancer (EPIC) Norfolk Phase 5 Study; Investigating repeat measures of physical and cognitive function performance in an existing cohort to characterise longitudinal trajectories and to understand their determinants.
IRAS ID
205471
Contact name
Carolyn Read
Contact email
Sponsor organisation
University of Cambridge
Duration of Study in the UK
2 years, 6 months, 31 days
Research summary
EPIC-Norfolk is an observational longitudinal study which recruited participants at baseline (1993 to 1997) from 35 participating general practices in Norfolk. Individuals provided information about lifestyle behavioural factors including diet and activity and attended a baseline health check (1HC). Participants have been re-invited to attend a number of health checks (2HC 1998-2001, 3HC 2004-2011 and 4HC 2012-2016), where baseline measures were repeated and as the study remit broadened, additional measurements added.
The proposed project, the EPIC-Norfolk Fifth Health Check (5HC) is funded by the Medical Research Council (MRC) with the overall aim of following up existing EPIC-Norfolk participants to obtain repeat measures of cognitive function, physical performance, physical activity and body composition to determine factors that influence the ageing process and risk of disease and disability. The collection of longitudinal data in this population, together with additional information on potential determinants, will provide a platform for future analyses of possible modifying factors for cognition, activity and sedentary behaviour and will inform the development of possible interventions to improve health and quality of life in older people.
REC name
East of England - Cambridge East Research Ethics Committee
REC reference
16/EE/0259
Date of REC Opinion
8 Aug 2016
REC opinion
Further Information Favourable Opinion