The effects of obesity surgery on gut hormones and metabolic factors

• Research type

  Research Study

• Full title

  The effects of obesity surgery on gut hormones and metabolic factors within the body

• IRAS ID

  158332

• Contact name

  Karim Meeran

• Sponsor organisation

  AHSC Joint Research Compliance Office, Imperial College London

• Duration of Study in the UK

  4 years, 0 months, 1 days

• Research summary

  Research has shown that obesity surgery is a highly effective way of promoting weight loss. Furthermore, it is known that obesity surgery can have a number of extended beneficial health effects. For example, it can attenuate the metabolic effects of type 2 diabetes to a certain extent and improve the cardiovascular health of patients. It is thought that these effects are not simply caused by a reduction in the absorption of food from the gut but actually due to more complex changes, including an effect on the nervous system within the gut and on the hormones produced by the body in response to food. These hormones and factors are produced at various sites within the body including within the gut. This study will assess the effects of the different types of weight loss surgery on patients' metabolic profiles, and whether the levels of any of these hormones or metabolic factors can predict which patients will respond best to such surgery.

• REC name

  London - West London & GTAC Research Ethics Committee

• REC reference

  14/LO/2233

• Date of REC Opinion

  23 Dec 2014

• REC opinion

  Favourable Opinion