The Effects of Modafanil on Surgical Error Rate

• Research type

  Research Study

• Full title

  The Effects of Pharmacological Enhancement on Surgical Error Rate

• IRAS ID

  199407

• Contact name

  Hajra Ashraf

• Contact email

  ashrafhajra@gmail.com

• Sponsor organisation

  Imperial College London

• Clinicaltrials.gov Identifier

  16/LO/1204 , London - Riverside Research Ethics Committee

• Duration of Study in the UK

  1 years, 0 months, 1 days

• Research summary

  This research study will be looking at the effects of the drug Modafinil (which is usually used to promote wakefulness in narcoplesy patients) on error rate. The study will recruit trainee surgeons and ask them to undertake a laparoscopic cholecystectomy on a simulator. During the time the participants gaze behaviour and task performance metrics will be documented. After initially completing the task (which should take no longer than 15 mins) the participant will be given an oral medication. This will either be 200mg of Modafinil or it will be a placebo. The participant will then have to wait approximately 2 hours to allow for maximum plasma concentration of Modafinil after which the task will be repeated and all metrics will be recorded once again. The two sets of data will then be analysed to identify whether there was any change in error rate and gaze behaviour between the Modafinil and Placebo group.

• REC name

  London - Riverside Research Ethics Committee

• REC reference

  16/LO/1204

• Date of REC Opinion

  18 Jul 2016

• REC opinion

  Unfavourable Opinion