The effect of airflow obstruction on coronary artery disease

• Research type

  Research Study

• Full title

  Investigation of the effect of airflow obstruction on the severity and type of coronary artery disease in people undergoing coronary angiography

• IRAS ID

  168076

• Contact name

  Emma Baker

• Contact email

  ebaker@sgul.ac.uk

• Sponsor organisation

  St George's, University of London

• Duration of Study in the UK

  1 years, 0 months, 5 days

• Research summary

  Coronary artery disease (hardening of the arteries supplying blood to the heart) is more common in people with lung disease than in those without. We still don’t fully understand why this is. The purpose of this study is to compare the type and severity of coronary artery disease in patients with and without lung disease as a first step to understanding why these two conditions are connected. We hope this will help patients with both conditions in the future. All patients attending for elective angiogram at St Georges Hospital are eligible for the study provided they are able and willing to give consent, are able to perform spirometry and have not had a chest infection (requiring antibiotics) within the last 6 weeks
  The investigator will spend approximately 10 minutes with eligible patients. All investigations can be performed on the ward at the bedside. The patient will answer 2 short questionnaires with the help of the researcher. The questionnaires specifically focus on health, activity and breathing.
  Waist and hip measurements will be performed. This will be performed standing or lying down, whichever is more comfortable. The patients will be asked to perform a spirometry test. This involves sitting or standing up, taking a deep breath in and blowing out as hard and for as long as possible. This is performed 3 times if possible and the best value is used as the reading. The researcher will also look at the patient’s records and collect some information about previous diseases, medication and blood test results. An extra tablespoon of blood will be taken from the patient when the cannula (small plastic tube) is inserted prior to the angiogram. The results of the angiogram will be used in the study
  The estimated duration of recruitment process is 6 months

• REC name

  West of Scotland REC 5

• REC reference

  14/WS/1158

• Date of REC Opinion

  17 Dec 2014

• REC opinion

  Further Information Favourable Opinion