The Edinburgh Type 2 Diabetes Study 10 year follow up - Version 1

• Research type

  Research Study

• Full title

  Risk factors for cognitive decline in people with type 2 diabetes; the Edinburgh Type 2 Diabetes Study 10 year follow-up (Version 1)

• IRAS ID

  194995

• Contact name

  Jackie Price

• Contact email

  Jackie.Price@ed.ac.uk

• Sponsor organisation

  University of Edinburgh

• Duration of Study in the UK

  15 years, 0 months, 0 days

• Research summary

  We find ourselves in an aging society, where dementia and cognitive decline are beginning to emerge as the next epidemic and are set to become a major challenge to healthcare providers. Diabetes is a well established risk factor for cognitive decline and the risk of dementia in people with diabetes is around 1.5 to 2.5 times that in the general population. It is now recognised that the effect of diabetes on cognitive decline is likely to be multifactorial, but the precise risk factors and how they might interact in order to increase disease risk is unknown.
  In 2006, with funding from the MRC, we set up a large, prospective, observational study (the Edinburgh Type 2 Diabetes Study) to identify risk factors for accelerated cognitive decline in older people with type 2 diabetes. 1066 men and women aged 60 to 75 years were recruited from the Lothian Diabetes Register and have been investigated for cognitive ability and potential disease risk factors and co-morbidities during three previous phases of data collection, in 2006/7, 2007/8 and 2012/13. The purpose of the current 10-year follow-up phase of the study is to re-cognitively test surviving participants in order to further investigate potential risk factors associated with long-term cognitive decline (i.e. using data collected over a 10-year period). Also to supplement existing study-specific bio-banks with 10-year samples and continue with data analysis on the extensive data resource which has now built up on the cognitive, vascular and non-vascular complications of type 2 diabetes.

• REC name

  South East Scotland REC 01

• REC reference

  16/SS/0098

• Date of REC Opinion

  23 May 2016

• REC opinion

  Further Information Favourable Opinion