The Early & Intensive SCI-MT Trial
Research type
Research Study
Full title
Early and intensive motor training (versus usual care) to enhance neurological recovery and function in people with spinal cord injury (SCI): The Early & Intensive SCI-MT Trial
IRAS ID
299991
Contact name
Claire Lincoln
Contact email
Sponsor organisation
NHS Greater Glasgow & Clyde
Clinicaltrials.gov Identifier
ACTRN12621000091808, Australian and New Zealand Clinical Trials Registry; U1111-1264-1689, Universal Trial
Duration of Study in the UK
3 years, 8 months, 1 days
Research summary
Treatments that promote neurological recovery, reduce paralysis and increase function are needed for people with SCI. The most promising and readily implementable intervention that could make a lasting difference to the lives of people with SCI is early and intensive motor training directed at recovery below the level of the injury. The aim therefore of The Early & Intensive SCI-MT Trial is to determine the effectiveness of early and intensive motor training on neurological recovery and function in people with SCI. A multi-centred international pragmatic randomised controlled trial will compare 10 weeks of early and intensive motor training with usual care for people with recent SCI. The primary endpoint will be motor recovery at 10 weeks. Secondary endpoints will be other measures of neurological status, function, time to discharge, ability to walk, psychological status, spasticity, pain and participants’ impressions of therapeutic benefit/change at 10 weeks and 6 months.
REC name
Yorkshire & The Humber - Bradford Leeds Research Ethics Committee
REC reference
21/YH/0306
Date of REC Opinion
20 Dec 2021
REC opinion
Favourable Opinion