The Developing Human Connectome Project: genetic & epigenetic analysis
Research type
Research Study
Full title
The Developing Human Connectome Project: genetic and epigenetic analysis
IRAS ID
248510
Contact name
David Edwards
Contact email
Sponsor organisation
King's College London
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
10 years, 0 months, 1 days
Research summary
We have previously shown that combining imaging data with collateral data, including genetic information, is a powerful strategy for discovering biological mechanisms of abnormal brain development. The Developing Human Connectome Project provides the largest, most advanced and most comprehensive set of neuroimaging and collateral data in the perinatal period that has yet been collected, and offers an unparalleled opportunity to develop these insights further. This observational study aims to capture a wide spectrum of human variability, including infants at high risk of neurodevelopmental and neurocognitive disorder. Genetic and epigenetic data when paired with MRI data will produce valuable insights into brain development allowing us to learn about the role of our genes in normal and abnormal brain development.
REC name
London - Central Research Ethics Committee
REC reference
18/LO/1512
Date of REC Opinion
13 Aug 2018
REC opinion
Favourable Opinion