The DANA Study
Research type
Research Study
Full title
Defining Disease Activity in Neovascular Age-related Macular Degeneration with Optical Coherence Tomography Angiography – A Prospective, Imaging Study – The DANA study
IRAS ID
263877
Contact name
Praveen Patel
Contact email
Sponsor organisation
Moorfields Eye Hosptial
Duration of Study in the UK
1 years, 5 months, 1 days
Research summary
This study is to find out whether using an extra type of scan called Optical Coherence Tomography Angiography (“OCTA”) will help to find new information to help doctors understand when to continue with eye injections and when it might be safe to stop treatment. This scan helps assess blood flow in the area of wet Age Related Macular Degeneration. This is particularly important as doctors want to minimise the number of eye injections wet AMD patients need so that side-effects of the injections are kept to a minimum.\nA total number of 150 eligible patients will be selected to join the study and images will be taken at two visits approximately six months apart.\nPatients will be selected from our internal register of potential subjects who meet the pre-screening inclusion criteria. These patients would have previously specified that they are happy to be contacted for research purposes. We anticipate that it will take 18 months to recruit our desired sample size of 150 patients. Patients will be in follow up for a period of six months. The study will conclude when the final patient visit has occurred.
REC name
North of Scotland Research Ethics Committee 1
REC reference
19/NS/0114
Date of REC Opinion
26 Jun 2019
REC opinion
Favourable Opinion