The CNS Integrase Inhibitor Study

  • Research type

    Research Study

  • Full title

    The Central Nervous System Effects of Two Different HIV-Integrase Inhibitor Containing Antiretroviral Regimens.

  • IRAS ID

    163720

  • Contact name

    Alan Winston

  • Contact email

    a.winston@imperial.ac.uk

  • Sponsor organisation

    Imperial College London

  • Eudract number

    2014-003710-84

  • Duration of Study in the UK

    0 years, 11 months, 31 days

  • Research summary

    Current anti-HIV therapy (antiretroviral therapy) is very effective in controlling the HIV virus and so keeping patients well. But there is still much we don’t know about how taking the drugs affect some parts of the body such as the brain. It is important that we learn more about how much of the newer drugs get into this area and what effect this has.
    The purpose of the study is to look at the differences in brain function between patients taking two different medications, which belong to the same new family of anti-HIV drugs called ‘integrase inhibitors’.

  • REC name

    London - Central Research Ethics Committee

  • REC reference

    14/LO/1864

  • Date of REC Opinion

    3 Nov 2014

  • REC opinion

    Favourable Opinion