The CAPRICORN Study

• Research type

  Research Study

• Full title

  The CAPRICORN Study - Critical Analysis of Patients with type 2 diabetes Reaching Important Clinical Outcomes Requiring New intervention

• IRAS ID

  156266

• Contact name

  Jaiveer Krishnan

• Contact email

  jaiveer.krishnan@geh.nhs.uk

• Sponsor organisation

  The University of Warwick

• Research summary

  Research question: Why would patients with type 2 diabetes develop avoidable complications in a real-life setting?

  Research hypothesis: Patients with type 2 diabetes develop complications due to the following factors:
  • Inadequately controlled risk factors, for example: higher blood pressure, higher cholesterol or higher blood sugar.
  • Failure of combined risk factor control (such as blood pressure, blood sugar & cholesterol)
  • Presence of non-traditional risk factors, for example: psychosocial risk factors such as mental health disorders requiring treatment and socio-economic status.

  Objectives: The CAPRICORN (Critical Analysis of Patients with type 2 diabetes Reaching Important Clinical Outcomes Requiring New intervention) study will be used to
  • Analyse relative impact of traditional risk factors (blood pressure, cholesterol and blood sugar) control in patients developing incident complications.
  • Assess the percentage of patients with complications who achieved single or combination risk factors within target compared to patients without complications, and
  • Assess contribution of other possible non-traditional risk factors in real-life setting

  Methodology: A case control study in patients with type 2 diabetes is proposed to achieve the objectives of the project. All patients with diabetes are treated following the NICE (National Institute of Health and Clinical Excellence) guidelines with its process outcomes measured by the QOF (Quality and Outcome Framework). This study is to identify the risk factors that may predict patients with type 2 diabetes who are more likely to develop avoidable complications such as admission for hypoglycaemia or diabetic ketoacidosis, heart attacks, stroke, leg ulcers, eye/kidney diseases etc. Patient's medical record will be used to collate data. Results are then analysed with the help of a statistician

• REC name

  West Midlands - Solihull Research Ethics Committee

• REC reference

  14/WM/1119

• Date of REC Opinion

  21 Oct 2014

• REC opinion

  Further Information Favourable Opinion