The ARMS-HD Study

  • Research type

    Research Study

  • Full title

    Analysing Retinal Metabolism in Health & Disease - An Observational Study

  • IRAS ID

    354367

  • Contact name

    Saaeha Rauz

  • Contact email

    s.rauz@bham.ac.uk

  • Sponsor organisation

    University of Birmingham

  • Duration of Study in the UK

    5 years, 0 months, 1 days

  • Research summary

    The retina is the part of the eye that helps us see by detecting light and sending messages to the brain. Problems with the retina are common and can sometimes cause permanent vision loss. In the UK, the main causes of sight loss are age-related macular degeneration (which affects the centre of the retina) and diabetic eye disease. Other conditions, like inflammation in the eye (known as uveitis), can also damage the retina. Unfortunately, once the retina is damaged, it usually can’t be fixed, which means the vision loss can be permanent.

    This study aims to understand how the tiny energy-producing parts of cells, called mitochondria, behave in people with eye diseases. We will use images collected from routinely used medical imaging devices and a special medically approved scanner, called the OcuMet Beacon, to check how well the mitochondria in the retina are working in healthy populations and those at risk of developing retinal problems.

  • REC name

    North West - Liverpool Central Research Ethics Committee

  • REC reference

    26/NW/0150

  • Date of REC Opinion

    25 Jun 2026

  • REC opinion

    Further Information Favourable Opinion