The adherence to multivitamins and minerals following duodenal switch.
Research type
Research Study
Full title
The adherence to multivitamin and mineral supplements following duodenal switch bariatric surgery
IRAS ID
231025
Contact name
Shashivadan Hirani
Contact email
Sponsor organisation
City, University of London
Clinicaltrials.gov Identifier
17-SC-0428, South Central Hampshire B
Duration of Study in the UK
0 years, 3 months, 1 days
Research summary
This project aims to address the factors that affect the adherence of multivitamins and minerals supplementation in patients following duodenal switch bariatric surgery. The duodenal switch surgery is performed for weight loss by reducing the size of the stomach as well as bypassing approximately four-fifth of the small intestines. The small intestines carry the bile and pancreatic enzymes that are necessary for the breakdown and absorption of protein, calories, vitamins, minerals and fats. Therefore, bypassing the portion of small intestines results in a significant decrease in the absorption of calories, nutrients and vitamins, consequently, increasing the risk of trace metal and vitamin nutritional deficiencies. This can lead to physical and neurological complications including, optic nerve damage, reduction of bone density, night blindness/vision loss, anaemia and damage or disease to the peripheral nerves. Therefore, following duodenal switch surgery patients are advised to take complete multivitamin and mineral supplementation for life.
Non-compliance to the complete multivitamin and mineral supplements can affect a person’s health and well-being following duodenal switch surgery.
There may also be many factors attributing to non-compliance to supplementation following duodenal switch surgery.
This research will investigate patients following duodenal switch surgery over a period of ten years at a single bariatric unit in London. This will be a retrospective study extracting socio-demographic data from the medical notes of these patients, as well as comparing the vitamin and minerals blood results to patients self-reporting adherence to vitamin and mineral supplementation. Patients are seen 6 monthly post duodenal switch by a member of the bariatric clinical team. At these consultations questions on adherence of multivitamins and mineral supplementation are asked and responses are recorded in the patients’ medical notes. Blood tests are also done 6 monthly to monitor vitamin and mineral levels due to the level of malabsorption and risk of deficiencies following the duodenal switch. The results are recorded in the electronic patient records (EPR).REC name
London - Westminster Research Ethics Committee
REC reference
17/LO/1616
Date of REC Opinion
4 Dec 2017
REC opinion
Further Information Favourable Opinion