Telomere length in Cystic Fibrosis patients
Research type
Research Study
Full title
Telomere length in Cystic Fibrosis patients
IRAS ID
179414
Contact name
Jamie Duckers
Contact email
Duration of Study in the UK
0 years, 2 months, 3 days
Research summary
Cystic Fibrosis (CF) is the most common fatal inherited inherited disease in Caucasians. Currently there are around 9000 patients with CF in the UK (UK CF Registry) and each week 5 babies are born with CF and two patients with CF die in the UK. Currently there is no cure for patients with CF and the average life expectancy for a patient with CF in the UK is 41 years (UK CF Registry). The life expectancy has improved dramatically due to novel therapies as well as increased numbers of lung transplants being performed.
Researchers predict that children born in the 2000s are expected to survive into their 50s. With this shift to an older population we are likely to see the emergence of age related diseases such as cancer and as such there has been an interest in studying ageing in adults with Cystic Fibrosis. Telomeres cap the ends of chromosomes and can help give an insight into the ageing process.
REC name
North of Scotland Research Ethics Committee 2
REC reference
15/NS/0047
Date of REC Opinion
11 Jun 2015
REC opinion
Further Information Favourable Opinion