Teenage and Young Adult Cancer Survivor Study (TYACSS) - Renewal
Research type
Research Database
IRAS ID
185692
Contact name
Michael M Hawkins
Contact email
Research summary
TYACSS database
REC name
London - South East Research Ethics Committee
REC reference
16/LO/0895
Date of REC Opinion
21 Jun 2016
REC opinion
Favourable Opinion
Data collection arrangements
The original objectives of the research were to establish a database of almost 300,000 individuals diagnosed with cancer aged 15 to 39 years, in England and Wales, between 1971 and 2006 and to investigate the observed and expected risks of: specific causes of death, specific types of subsequent primary cancer and specific types of non-cancer morbidity (including cardiovascular, pulmonary, urological, hepatic and endocrine conditions). From such linkages it will be possible to identify subgroups of patients (defined in terms of type of cancer, age at treatment, calendar year of diagnosis, period of follow-up, attained age and sex) at a substantially increased risk of specific adverse health outcomes.
Record linkages between the established database and the national death and cancer registries, the Hospital Episode Statistics (HES) for England, the Patient Episode Database for Wales (PEDW) in Wales, the National Institute for Cardiovascular Outcomes Research (NICOR) and the Myocardial Ischaemia National Audit Project (MINAP) have been undertaken or are currently being undertaken.
Research programme
The study, originally funded by Cancer Research UK in 2010 and NIHR in 2012, will be the first comprehensive investigation of fatal and non-fatal serious adverse health outcomes of cancer treatment in teenagers and young adults and the population-based design and large sample size would undoubtedly lead to a landmark contribution.
Research database title
TYACSS database
Establishment organisation
The University of Birmingham
Establishment organisation address
Centre for Childhood Cancer Survivor Studies
Institute of Applied Health Research
Robert Aitken Building
B15 2TT