Technique development in MR scanning of volunteers inhaling Xe gas
Research type
Research Study
Full title
Technique development for MR scanning of volunteers using hyperpolarized Xenon gas
IRAS ID
184958
Contact name
Nicholas Screaton
Contact email
Sponsor organisation
Papworth NHS Foundation Trust
Duration of Study in the UK
2 years, 0 months, 0 days
Research summary
The aim of this study is to evaluate techniques for magnetic resonance imaging employing hyperpolarized Xenon gas as a contrast agent. This will be inhaled in low doses by the volunteers before they undergo an MR scan of their thorax. The Xenon gas acts as a contrast agent to show ventilation and perfusion defects in the lung and has many potential uses and clinical benefits. The procedures involved are established research techniques in use at other centres - however, this will be a new procedure at Papworth Hospital. We need to optimise certain parts of the technique using local equipment before embarking upon a clinical research study proper. This optimisation process requires the scanning of volunteers in order to give authentic imaging conditions.
REC name
East of England - Cambridge Central Research Ethics Committee
REC reference
15/EE/0280
Date of REC Opinion
20 Oct 2015
REC opinion
Further Information Favourable Opinion