Taxifolin/ergothioneine and immune biomarkers in healthy volunteers
Research type
Research Study
Full title
A study of dietary Taxifolin/Dihydroquercetin and Ergothioneine upon immune biomarkers in healthy volunteers.
IRAS ID
300322
Contact name
Caroline Childs
Contact email
Sponsor organisation
University of Southampton
Duration of Study in the UK
1 years, 6 months, 1 days
Research summary
A number of ingredients and foods can influence immune function by providing building blocks or by interacting with our gut bacteria. We will investigate whether Taxifolin or Ergothioneine can influence the immune system. Taxifolin is found in apples, onions and other fruits and bark extracts. Ergothioneine is found in mushrooms, oats and some bean varieties.
In this study, 90 adults aged 50-65yr will be given either 250mg/day Taxifolin, 80mg/day Ergothioneine, or a placebo for 8 weeks. We will collect blood samples to allow us to look closely at how their immune system is working, and will store faecal and urine samples which will allow us to find out whether their gut bacteria are interacting with these supplements.
REC name
London - City & East Research Ethics Committee
REC reference
21/LO/0504
Date of REC Opinion
7 Sep 2021
REC opinion
Further Information Favourable Opinion