SWiNd-MS Small Worlds in Neurodegeneration - Multiple Sclerosis Ver. 1

• Research type

  Research Study

• Full title

  SWiNd-MS Small Worlds in Neurodegeneration – Multiple Sclerosis Neurophysiological Exploration of Functionally Connected Networks in Multiple Sclerosis A Pilot Biomarker Study

• IRAS ID

  164258

• Contact name

  Luke Canham

• Contact email

  luke.canham@nbt.nhs.uk

• Sponsor organisation

  Research & Innovation, North Bristol NHS Trust

• Duration of Study in the UK

  0 years, 3 months, 2 days

• Research summary

  This pilot study is designed to evaluate the potential use of brain network measurements to serve as a surrogate biomarker of cognitive dysfunction in Multiple Sclerosis. This is important to facilitate clinical research for a currently untreatable problem. We plan to model brain networks and gauge their 'Small Worldness' with standard techniques using data from simple standard brainwave (EEG) recordings and compare this to performance on validated cognitive tests. This study involves a single visit, is of minimal burden and uses extremely safe non-invasive assessments.

• REC name

  HSC REC A

• REC reference

  15/NI/0042

• Date of REC Opinion

  9 Mar 2015

• REC opinion

  Further Information Favourable Opinion