Surgical management of Osteomyelitis using CERAMENT G

  • Research type

    Research Study

  • Full title

    Certitude - A Post-Market Prospective Cohort Study on Subjects Receiving CERAMENT G as Part of the Surgical Treatment of Osteomyelitis in a Single-stage Surgical Procedure

  • IRAS ID

    339381

  • Contact name

    Jamie Ferguson

  • Contact email

    jamie.ferguson@ouh.nhs.uk

  • Sponsor organisation

    BoneSupport AB

  • Clinicaltrials.gov Identifier

    NCT06555848

  • Duration of Study in the UK

    7 years, 1 months, 1 days

  • Research summary

    CERAMENT G, is an implantable bone void filler indicated for use as an adjunct to systemic antibiotic therapy and surgical debridement (standard treatment approach to a bone infection) where there is a defect in the bone following infection excision. Whilst this treatment has been previously studied, the purpose of this post market prospective cohort study is to obtain longer-term clinical and radiographic data on the safety and effectiveness of CERAMENT G as part of the surgical treatment of osteomyelitis in a single-stage procedure.
    Detailed questions to be answered are:
    1. What is the nature, severity, and frequency of incomplete new bone formation?
    2. What is the nature, severity, and frequency of the risks of probable adverse events and serious adverse events associated with incomplete new bone formation, including pathologic fractures and reinfection?

  • REC name

    North East - Newcastle & North Tyneside 1 Research Ethics Committee

  • REC reference

    24/NE/0167

  • Date of REC Opinion

    17 Sep 2024

  • REC opinion

    Favourable Opinion