Substrate use during prolonged exercise with ingestion of ethanol (v1)
Research type
Research Study
Full title
Glycogen metabolism during 2 hours of moderate intensity exercise in man following ingestion of alcohol.
IRAS ID
224412
Contact name
James A. Betts
Contact email
Duration of Study in the UK
1 years, 0 months, 0 days
Research summary
Ethanol is rich in energy and therefore provides fuel to the body much like fats and carbohydrates. It has been suggested that ethanol may spare the use of fats and carbohydrates up to a maximum level of half of all energy expended at rest. Very little research has investigated the effects of ethanol ingestion during times at which the body has an increased requirement for energy (e.g. during exercise). The proposed research seeks to investigate the influence of ethanol immediately prior to a bout of prolonged exercise on fat and carbohydrate metabolism. \n\nThe study will seek to recruit 16 healthy, active men, between the ages of 18-30 with no previous history of metabolic disease (e.g. diabetes) or substance abuse (alcohol/tobacco). Once enrolled, participants will be taken through preliminary fitness and body composition analysis (carried out by a dual energy x-ray absorptiometry [DEXA] scan) before performing two bouts of cycling exercise in a random order with maximum of 1 week break between visits. \n\nThe two sessions will consist of either: 2 hours exercise with ethanol ingestion; or 2 hours exercise with no ethanol ingestion. During these sessions muscle, blood, and breath samples will be collected in order to investigate the effects of ethanol on metabolism during exercise. \n\nAll testing for this research project will be carried out at the university of Bath with the aim to complete initial data collection by April 2018. \n
REC name
South West - Central Bristol Research Ethics Committee
REC reference
17/SW/0219
Date of REC Opinion
30 Oct 2017
REC opinion
Further Information Favourable Opinion