Study of Effectiveness and Safety of SD-101 in Subjects with Epidermolysis Bullosa

  • Research type

    Research Study

  • Full title

    A Phase 3, Multi-center, Randomized, Double-Blind, Placebo Controlled Study of the Efficacy and Safety of SD-101 Cream in Patients with Epidermolysis Bullosa

  • IRAS ID

    159482

  • Contact name

    Anna Martinez

  • Contact email

    Anna.Martinez@gosh.nhs.uk

  • Sponsor organisation

    Novella Clinical

  • Eudract number

    2014-002288-14

  • Research summary

    An investigation is being conducted to look into how safe and effective the study drug, SD-101, is in patients with Epidermolysis Bullosa.

    Epidermolysis Bullosa is an inherited skin fragility disorder which is both debilitating and life threatening. Currently, there is no standard of care therapy for this disease. The study drug is a cream which applied to the skin.

    This study will be for Epidermolysis Bullosa patients and those who choose to enrol onto the study will participate for approximately 90 days. During the study, patients will need to attend 5 outpatient visits, complete a medication diary and pain and itching scales and also apply the study drug cream all over their body once per day.

  • REC name

    London - Riverside Research Ethics Committee

  • REC reference

    14/LO/1293

  • Date of REC Opinion

    26 Sep 2014

  • REC opinion

    Further Information Favourable Opinion