Study of AMR in OPAT patients

• Research type

  Research Study

• Full title

  Evolution of antimicrobial resistance (AMR) in patients receiving Outpatient Parenteral Antimicrobial Therapy (OPAT)

• IRAS ID

  273856

• Contact name

  Estee Torok

• Contact email

  et317@cam.ac.uk

• Sponsor organisation

  CUH NHS Foundation Trust & University of Cambridge

• Duration of Study in the UK

  1 years, 6 months, 0 days

• Research summary

  This study explores how gut bacteria change and develop resistance in patients who have received long courses of intravenous antibiotics in the community.

  It compares bacteria in stool from participants who have received different intravenous antimicrobials (Out-Patient Antibiotic Clinic patients) to participants who have not (a control group.)

  Stool samples will be examined at enrolment, weekly during antimicrobial therapy, at 3 and 6 months. Demographic information and relevant medical history will be collected.

  This study will help future doctors choose better antimicrobials for Out-Patient Antibiotic Clinic patients and could reduce the spread of antimicrobial resistance in this group.

• REC name

  East Midlands - Derby Research Ethics Committee

• REC reference

  20/EM/0009

• Date of REC Opinion

  8 Jan 2020

• REC opinion

  Favourable Opinion