STRAT-PD
Research type
Research Study
Full title
Identification of biological indicators for disease in patients with Parkinson’s disease – The Breath Test Study
IRAS ID
186728
Contact name
Roger Barker
Contact email
Sponsor organisation
Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge
Duration of Study in the UK
2 years, 11 months, 31 days
Research summary
Parkinson's disease (PD) is the second most common neurodegenerative disease. Specific populations of cells in the brain die resulting in debilitating clinical features including a range of motor and non-motor problems. There are currently no disease modifying treatments for it and diagnosing the condition can be difficult, especially as there are different subtypes of patients with this condition. The main purpose of this current study is to evaluate the ability of the breath analysis technique in identifying combinations of Volatile Organic Compounds (VOCs) that can; (i) differentiate between people with/without PD; (ii) further discriminate between these proposed subtypes within the PD population; and (iii) track disease course. Interesting candidate VOCs will then be compared with existing clinical data, in order to identify compounds that may play a role in the pathogenesis of types of PD.
REC name
East of England - Cambridge South Research Ethics Committee
REC reference
15/EE/0393
Date of REC Opinion
19 Nov 2015
REC opinion
Further Information Favourable Opinion