SPRINT study
Research type
Research Study
Full title
Supplementation with PUFAs in Re-feeding and Improving post Necrotising enterocolitis feed Tolerance (SPRINT) study.
IRAS ID
187873
Contact name
Enitan Ogundipe
Contact email
Sponsor organisation
Chelsea and Westminster NHS Foundation Healthcare trust
Duration of Study in the UK
5 years, 0 months, 1 days
Research summary
This is a study to assess whether supplementation of infant milk with a food supplement polyunsaturated fatty acid PUFA) will improve feed tolerance in neonates who required surgery for treatment of necrotising enterocolitis (NEC) which is a multi-system disorder that results in gut necrosis and blood poisoning in vulnerable preterm babies. We would also study whether or not infants who receive the PUFA supplementation have better health outcomes in this study group e.g. reduced length of stay in hospital, less liver dysfunction and enhanced brain developmental outcomes.
The mothers of the babies enrlled in the study will also be requested to give a blood sample to check their lipid profiles which will be compared to that of their infants at enrolment and at 6 weeks post enrolment.REC name
London - City & East Research Ethics Committee
REC reference
17/LO/1453
Date of REC Opinion
21 Sep 2017
REC opinion
Unfavourable Opinion