Speech features in clinical depression 1.0

  • Research type

    Research Study

  • Full title

    Acoustic and perceptual features in clinical depression: A feasibility pilot study

  • IRAS ID

    239592

  • Contact name

    Hamish McAllister-Williams

  • Contact email

    r.h.mcallister-williams@ncl.ac.uk

  • Sponsor organisation

    Northumberland, Tyne & Wear NHS Foundation Trust

  • Duration of Study in the UK

    0 years, 6 months, 7 days

  • Research summary

    The proposed pilot study will investigate vocal characteristics within clinical depression, explore their role as potential indicators of symptom severity and the utilisation of a smartphone as a reliable method for voice data capture.

    The pilot study may potentially be linked to Study EME Ref: 16/44/22, a randomised control trial examining treatment response in depressed patients. As such, certain methodological choices, such as data collection points, and inclusion/exclusion criteria were selected to mirror those chosen for this larger study.

    Data will be collected from a clinical (i.e. depressed) and control group, with four time points for collection: baseline, 8 weeks, 16 weeks and 26 weeks. Participants will be required to complete assessments to determine symptom severity, and also provide voice samples collected simultaneously through a smartphone device and studio recording equipment.

    Exploratory analysis of voice features, including acoustic parameters (e.g. frequency, perturbation), perceptual aspects (e.g. articulator movement, phonation) and prosody will be undertaken with the aim of refining the number of variables to be investigated in future research. This project will also offer the opportunity to determine confidence interval estimation for different parameters within clinical and non-clinical samples. Furthermore, results from this pilot will provide information on length of time necessary for completion of in-depth vocal analysis per participant, and whether this method of analysis is feasible on a larger scale.

    A cross-recorder parallel validation will also take place, comparing the quality of acoustic outputs from both a smartphone device and studio recording equipment. Results will provide justification for the use of a smartphone device as a reliable method of data capture for future research in depressed populations.

  • REC name

    North East - Newcastle & North Tyneside 1 Research Ethics Committee

  • REC reference

    18/NE/0129

  • Date of REC Opinion

    12 Jul 2018

  • REC opinion

    Further Information Favourable Opinion