SPEAK-2: Surveying People Experiencing young Adult Kidney failure
Research type
Research Study
Full title
SPEAK-2: Surveying People Experiencing young Adult Kidney failure - five year follow-up study
IRAS ID
274413
Contact name
Mohammed Al-Talib
Contact email
Sponsor organisation
University of Bristol
Duration of Study in the UK
0 years, 10 months, 28 days
Research summary
In the SPEAK study, we surveyed young people with kidney transplants or on dialysis and found impaired independence and employment, poor quality of life, mental wellbeing and mental health when compared to the general population. We saw poorer outcomes for young adults on dialysis compared to those with a kidney transplant.
Five years on, we now wish to follow up these patients in SPEAK-2.
Specifically, we want to find out whether being on dialysis is the cause of poorer psychological health, or whether this may be caused by other factors such as a lack of support, poor compliance or other medical problems. Evidence that a particular treatment is associated with poorer outcomes provides the justification for increased support and makes finding interventions to improve outcomes a priority.
We have permission to contact our original study recruits again having specifically consented for this in the original SPEAK study, which will allow us to transform the original cross-sectional study into a cohort study with a view to ongoing longitudinal follow-up.
We will use statistics to assess the importance of treatment changes and time period on the baseline and 5-year outcomes. This will tell us whether changing treatment is a risk factor for poorer psychosocial health outcomes, and whether this should be an opportunity to assess patients in their routine clinical care and intervene if necessary. From this work we ultimately would aim to identify and develop interventions that are targeted to best address the issues identified.REC name
London - Brent Research Ethics Committee
REC reference
20/LO/0534
Date of REC Opinion
29 May 2020
REC opinion
Favourable Opinion