Southampton Arm Fracture Study

  • Research type

    Research Study

  • Full title

    Assessment of patients aged 65+ years with an upper limb fracture for frailty and sarcopenia for the prevention of future falls and fractures: a feasibility study

  • IRAS ID

    247077

  • Contact name

    Helen Roberts

  • Contact email

    hcr@soton.ac.uk

  • Sponsor organisation

    University Hospital Southampton Foundation Trust

  • Clinicaltrials.gov Identifier

    35149, The ISRCTN register created on 16/04/2018

  • Duration of Study in the UK

    2 years, 4 months, days

  • Research summary

    A third of people aged over 65 years fall every year, leading to fractures in
    10-15%. Arm fractures are often the first sign of fragile bones
    (osteoporosis). 25% of these patients will suffer another fracture, often of
    the hip, within 10 years. National guidelines recommend routine
    assessment of people with arm fractures for fragile bones to help prevent
    subsequent hip fractures.
    The risk of falling is increased in people who are frail or have lost muscle
    strength with ageing (sarcopenia). Both of these conditions are more
    common in patients who suffer from fragile bones. Identifying and
    managing frailty or sarcopenia when we age could reduce future falls and
    fractures.
    We will study 120 people aged 65 or over with an arm fracture from three
    fracture clinics in one city in England. We will see if it is feasible and
    acceptable to assess frailty and sarcopenia in a busy fracture clinic in
    addition to assessing for fragile bones. We will determine the feasibility of
    referring patients with frailty or sarcopenia to specialist services for older
    patients for appropriate therapy and advice. This will provide information
    for a future trial to establish if falls and fractures can be prevented.
    We will assess patients in the study for frailty and sarcopenia using
    questionnaires and physical measurements. This will allow us determine
    the most practical measures to be used in clinic and how common frailty
    and sarcopenia are among this population.
    We will collect information on falls, fractures, health and social care input
    over six months, and measure patient’s quality of life. Interviews with
    patients and staff members will establish the acceptability of these
    additional assessments.
    This study has Public Involvement throughout, including steering group
    membership, co-design of questionnaires and patient information leaflets,

  • REC name

    North East - Newcastle & North Tyneside 1 Research Ethics Committee

  • REC reference

    18/NE/0377

  • Date of REC Opinion

    13 Dec 2018

  • REC opinion

    Favourable Opinion