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Mature Lymphoid Malignancies observation study

  • Research type

    Research Study

  • Full title

    A longitudinal observational study with phenotypic, functional and molecular characterization of the tumor lymphoid cells in patients with mature lymphoid malignancies in the South Coast



  • Contact name

    Francesco Forconi

  • Contact email

  • Sponsor organisation

    University of Southampton

  • Identifier

    LLR renewal application 2015, 971

  • Duration of Study in the UK

    8 years, 2 months, 20 days

  • Research summary

    The purposes of this study are I) to determine the characteristics of the tumour cells that can predict clinical outcome of patients with lymphomas and leukaemias, ii) to provide biological material to clinicians and scientists who participate to the activity of the "South Coast Tissue Bank" through a centralised rigorous scientific and ethical review process, iii) to perform a panel of established tests on those patients with chronic lymphocytic leukaemia and lymphoproliferative disorders. This will enable researchers to request those samples most suitable for their research. This study will provide a unique source of tumour cells from patients, of which long longitudinal follow up. The project will have the potential of discovering and validation characteristics that distinguish less aggressive tumours and more aggressive tumours and may offer the possibility of the development of a diagnostic tests.

  • REC name

    South Central - Hampshire B Research Ethics Committee

  • REC reference


  • Date of REC Opinion

    16 May 2016

  • REC opinion

    Further Information Favourable Opinion