Sourcing Skeletal Muscle

  • Research type

    Research Study

  • Full title

    Sourcing skeletal muscle project: collection of skeletal muscle from donated kidney transplants

  • IRAS ID

    327294

  • Contact name

    Colin Wilson

  • Contact email

    colin.wilson6@nhs.net

  • Sponsor organisation

    The Newcastle upon Tyne Hospitals NHS Foundation Trust

  • Duration of Study in the UK

    1 years, 11 months, 30 days

  • Research summary

    This project seeks to collect and store muscle samples (psoas muscle) that are usually discarded from donor kidneys during preparation for transplant. These stored muscle samples will provide an important resource for future research into skeletal muscle studies, helping to understand how skeletal muscle changes at different stages of life.

    Kidney transplant recipients will be asked for their consent for using these discarded samples, but no study procedures will be applied to transplant recipients. No changes to the preparation of donor kidneys are envisaged; these muscle samples are currently removed by the surgical team during preparation of the donor kidney for
    transplant.

    The transplant surgical team at the Freeman will remove the muscle samples from the donor kidney as part of usual clinical care. These samples will then be collected by the research nurse team, frozen and transferred for storage in the Newcastle Biobank. Information that accompanies the donor organ will be stored on a RedCAP database held by Newcastle Hospitals, along with a unique project ID for each sample.

  • REC name

    London - Bromley Research Ethics Committee

  • REC reference

    24/PR/1247

  • Date of REC Opinion

    22 Oct 2024

  • REC opinion

    Favourable Opinion