SoundMind-MCI
Research type
Research Study
Full title
Sound entrainment of brain oscillations in mild cognitive impairment
IRAS ID
320617
Contact name
Gráinne McLoughlin
Contact email
Sponsor organisation
King's College London
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
0 years, 10 months, 31 days
Research summary
Our research aims to explore a novel approach for easing symptoms associated with mild cognitive impairment (MCI) and its relevance to individuals affected by dementia. We are investigating a non-invasive method called Continuous Amplitude Modulated Sound Stimulation (CAMSS) that aims to modulate brainwaves in specific frequencies using everyday sounds. Unlike conventional methods that use artificial sounds, CAMSS seamlessly embeds these frequencies into familiar environmental sounds, making the auditory experience natural and unobtrusive for individuals with MCI. This research holds immense importance for individuals dealing with dementia-related conditions. By introducing a simple method—listening to modified sounds—we aim to offer a new accessible way to alleviate dementia symptoms, potentially enhancing the quality of life for those affected. We're focusing on studying dementia-related cognitive impairment without testing any specific drug, device, or medical procedure. Instead, we're exploring the effects of sound on brainwaves and cognition in individuals with MCI. Our study will involve 30 participants diagnosed with MCI. Participants will engage in a single session lasting approximately 2 to 2.5 hours at King’s College London. During this time, they will undergo brain imaging, specifically, electroencephalogram (EEG) monitoring, while listening to different types of sounds. Additionally, they will perform cognitive tasks designed to assess attention, memory, and cognitive control. This research is industry funded by the Chen Institute. In summary, our investigation into CAMSS offers a promising avenue for exploring new, non-invasive ways to potentially improve cognitive symptoms in individuals with MCI. This research underscores the importance of accessible ways to positively impact the lives of those affected by dementia-related conditions.
REC name
London - Brent Research Ethics Committee
REC reference
24/PR/0231
Date of REC Opinion
2 Apr 2024
REC opinion
Favourable Opinion