Smartphone Brainwave Entrainment Technology in chronic pain v1.3
Research type
Research Study
Full title
A feasibility study of smartphone-based brainwave entrainment (BWE) technology as a novel treatment for chronic pain
IRAS ID
271075
Contact name
Anthony KP Jones
Contact email
Sponsor organisation
University of Manchester
Clinicaltrials.gov Identifier
Duration of Study in the UK
3 years, 0 months, 3 days
Research summary
Is brainwave entrainment a feasible tool for managing long-term pain in a patient population in the home-setting?
Long-term pain affects 4 in 10 people in the UK and can impact on all aspects of life. Many people find that their pain is not well controlled on the treatments that are currently available, or they experience unpleasant side-effects from painkillers. There is therefore an urgent need for new safe and effective treatments for long-term pain.
One new approach to treatment is to target alpha brainwaves - rhythmic brain activity that is known to be associated with reduced pain. Alpha brainwaves can be increased by looking at flashing lights or listening to rhythmic sounds at the same rhythm as the brainwaves. This is known as “brainwave entrainment” and can be delivered through a smartphone application.
The aim of this study is to test the suitability, acceptability and benefits of the brainwave entrainment smartphone application for people with long-term pain, and to inform the design of a future larger study.
We aim to recruit 30 participants. Individuals may be eligible if they are over 18 years old and have suffered persistent pain for longer than 3 months. Participants will attend a 3-hour session in the laboratory in either Manchester or Leeds. They will undergo brainwave entrainment for different lengths of time whilst their brain activity and pain levels are recorded to determine the most effective “dose” of entrainment for that individual. They will then use the smartphone application at home 3 times a day for 4 weeks, and will complete pain, sleep, fatigue and quality of life questionnaires. At the end of the study, we will conduct interviews to gain in-depth feedback. The total duration for each participant is around 7 weeks.
This study is funded by a Leeds Cares Clinical Research Fellowship.REC name
North West - Greater Manchester East Research Ethics Committee
REC reference
20/NW/0199
Date of REC Opinion
22 Jun 2020
REC opinion
Further Information Favourable Opinion