Smart Matrix, version number 1.0, date 30 March 2018

  • Research type

    Research Study

  • Full title

    Study Assessing the Safety and Performance of Smart Matrix® Dermal Replacement Scaffold in the Treatment of Full-Thickness Wounds Arising From Surgical Excision of Basal Cell or Squamous Cell Carcinomas in Male and Female Adult Patients

  • IRAS ID

    245749

  • Contact name

    Lilian Hook

  • Contact email

    hookl@smartmatrix.co.uk

  • Sponsor organisation

    Smart Matrix Limited

  • Clinicaltrials.gov Identifier

    NCT03742726

  • Clinicaltrials.gov Identifier

    -, -

  • Duration of Study in the UK

    2 years, 0 months, 0 days

  • Research summary

    Indication(s) for Use: Full-thickness wounds, such as those following excision of basal cell carcinoma or squamous cell carcinoma, and surgically excised full- and partial thickness burn wounds. Smart Matrix should be used in conjunction with standard wound care regimes.

    Smart Matrix is a medical device intended for the management of wounds, including reconstructive treatment of full- and partial-thickness wounds and first and second degree burns, without the use of a split thickness skin graft in adults.

    Patients who meet the inclusion and exclusion criteria will be considered eligible for the study.

    From first enrolment to last patient last visit, the study duration is expected to be approximately 2 years, with 1 year of enrolment.

    Patients will undergo physical examination, vital signs, serum pregnancy test (women of childbearing potential only), clinical laboratory analytes, photography/measurement of wound, assessment of pain at dressing change and between visits, scar assessment.

  • REC name

    West Midlands - South Birmingham Research Ethics Committee

  • REC reference

    18/WM/0143

  • Date of REC Opinion

    26 Jun 2018

  • REC opinion

    Further Information Favourable Opinion