Sloan Water Technology Ltd. LAWS pre-clinical testing

  • Research type

    Research Study

  • Full title

    Liquid Acoustic Wound Stream (LAWS) pre-clinical safety and efficacy testing



  • Contact name

    Thomas Secker

  • Contact email

  • Sponsor organisation

    Sloan Water Technology Ltd.

  • Duration of Study in the UK

    1 years, 9 months, 31 days

  • Research summary

    Sloan Water Technology are developing a novel wound therapeutic device, the Liquid Acoustic Wound Stream (LAWS). The LAWS device produces a gentle stream of saline containing acoustically activated bubbles and is used to promote wound healing through the removal of bacteria, biofilms, and other contaminants and pathogens without damaging underlying healthy tissue. This cleaning action will further reduce biochemical and cellular debris that impair healing which is pertinent to both acute and chronic wounds.

    The LAWS device uses bagged saline delivered through an easy-to-operate and position nozzle that applies the therapeutic activated saline to the wound and surrounding tissue making it simple to use, even on patients with limited mobility. The device consists of elements that deliver the saline, generate an acoustic signal and activated bubbles that will travel down the gentle saline stream to the wound bed. The acoustically excited bubbles will be drawn to the tissue surface and wound crevices through Bjerknes forces. There surface waves excited on the bubble walls will generate local shear forces that detach bioburden, irrigate the wound, and sound waves travelling though the saline stimulate cells to promote the healing response.

    This project involves the preclinical testing of the healing aspects of the LAWS device. In brief, the LAWS device will be used to treat human surgically salvaged skin samples that are purchased and supplied by the company Genoskin (France). The treated skin will be histologically examined for healing response and tissue safety, further analysis will determine the mechanisms of healing. The data collected will be used to guide design decisions and will be part of the documentation compiled to submit an application to the MHRA.

  • REC name

    London - South East Research Ethics Committee

  • REC reference


  • Date of REC Opinion

    2 Feb 2024

  • REC opinion

    Favourable Opinion