SLK Study

• Research type

  Research Study

• Full title

  Prospective observational study to identify meibomian gland inversion (MGI) / upper marginal entropion in patients with superior limbic keratoconjunctivitis (SLK)

• IRAS ID

  291098

• Contact name

  Raman Malhotra

• Contact email

  raman.malhotra1@nhs.net

• Sponsor organisation

  Research & Development, Queen Victoria Hospital NHS Foundation Trust

• Duration of Study in the UK

  0 years, 5 months, 30 days

• Research summary

  The Corneoplastic Unit at the Queen Victoria Hospital often manages patients with superior limbic keratoconjunctivitis (SLK). We hypothesise that meibomian gland inversion (MGI) and/or upper marginal entropion is a major contributing factor in the development of SLK, and is currently under-recognised. This prospective observational cohort study aims to answer the research question: "Is MGI or upper marginal entropion a contributing factor in the development of SLK?". This study will take place over six months, within the Ophthalmology department of an NHS site, and include all patients identified as possessing features of SLK.

• REC name

  South West - Cornwall & Plymouth Research Ethics Committee

• REC reference

  21/SW/0014

• Date of REC Opinion

  26 Jan 2021

• REC opinion

  Favourable Opinion